Sunday, July 31, 2016

Paternal Nutrition and Daughter's Risk

Scripture of the Day:
Luke 4:40
Now when the sun was setting, all they had sick with divers diseases  brought them unto him, and he laid his hands on them and healed them.

I'm finding many interesting things about breast cancer and what researchers think. Some of it is quite frightening. I'm not sure I'm in with some of it. I've read that they blame it on smoking, obesity, heredity, and environmental. Now this article about paternal influences. Sadly, what it boils down to is that there is no way to avoid the possibility of breast cancer or any other cancer. The link to this article is at the bottom of the page.

Paternal programming of breast cancer risk in daughters...


  • Camile Castilho Fontelles,
  • Luiza Nicolosi Guido,
  • Mariana Papaléo Rosim,
  • Fábia de Oliveira Andrade,
  • Lu Jin,
  • Jessica Inchauspe,
  • Vanessa Cardoso Pires,
  • Inar Alves de Castro,
  • Leena Hilakivi-Clarke,
  • Sonia de Assis and 
  • Thomas Prates Ong


    Background

    Although males contribute half of the embryo’s genome, only recently has interest begun to be directed toward the potential impact of paternal experiences on the health of offspring. While there is evidence that paternal malnutrition may increase offspring susceptibility to metabolic diseases, the influence of paternal factors on a daughter’s breast cancer risk has been examined in few studies..

    Methods

    Male Sprague-Dawley rats were fed, before and during puberty, either a lard-based (high in saturated fats) or a corn oil-based (high in n-6 polyunsaturated fats) high-fat diet (60 % of fat-derived energy). Control animals were fed an AIN-93G control diet (16 % of fat-derived energy). Their 50-day-old female offspring fed only a commercial diet were subjected to the classical model of mammary carcinogenesis based on 7,12-dimethylbenz[a]anthracene initiation, and mammary tumor development was evaluated. Sperm cells and mammary gland tissue were subjected to cellular and molecular analysis.

    Results

    Compared with female offspring of control diet-fed male rats, offspring of lard-fed male rats did not differ in tumor latency, growth, or multiplicity. However, female offspring of lard-fed male rats had increased elongation of the mammary epithelial tree, number of terminal end buds, and tumor incidence compared with both female offspring of control diet-fed and corn oil-fed male rats. Compared with female offspring of control diet-fed male rats, female offspring of corn oil-fed male rats showed decreased tumor growth but no difference regarding tumor incidence, latency, or multiplicity. Additionally, female offspring of corn oil-fed male rats had longer tumor latency as well as decreased tumor growth and multiplicity compared with female offspring of lard-fed male rats. Paternal consumption of animal- or plant-based high-fat diets elicited opposing effects, with lard rich in saturated fatty acids increasing breast cancer risk in offspring and corn oil rich in n-6 polyunsaturated fatty acids decreasing it. These effects could be linked to alterations in microRNA expression in fathers’ sperm and their daughters’ mammary glands, and to modifications in breast cancer-related protein expression in this tissue.
    If you are making this journey as I am, may God bless you with His healing touch. I know He loves you.

    Sunday, July 24, 2016

    6 Behaviors that Cancer Survivors Have in Common

    Scripture of the Day:

    Matthew 8: 16

    And when evening was come, they brought unto Him many that were possessed devils: and he cast out the spirits with His word; and healed all that were sick.


    These are all true for me except the first one. I tried all that but I ate pretty healthy to start with. But no matter how I ate and how much I exercise, I could not lose the weight. I found that in some the cancer medication I was on (Letrozol) had weight gain as a side effect. Now that I'm off, I'm noticing a difference in that too. The following link will take you to this article. It may help you whether  you are fighting breast cancer or another life changing event. 


    6 Behaviors these Cancer Survivors have in Common





    Dr. Kelly Turner, a PhD who trained at Harvard and UC Berkeley

    1. They changed their diets. 

    The majority of Dr. Turner’s interviewees credited diet change as a powerful tool for self-healing. Most recommended eating a diet consisting primarily of whole vegetables, fruits, grains, and beans, while eliminating meat, sugar, dairy, and refined grains. When your body’s innate self-repair mechanisms are overtaxed with cleaning up toxins from a poor diet, it’s hard for them to go about the business of fighting cancer. But when your diet is pristine, your natural self-repair mechanisms can do what they know how to do - kill cancer cells and try to return the body to homeostasis. For great examples of how to fight cancer with a vegan, largely raw, chemical-free, anti-inflammatory diet, check out Kris Carr’s Crazy Sexy Diet and Crazy Sexy Kitchen.

    2. They deepened their spirituality. 

    Many of Dr. Turner’s interviewees discussed feeling an internal sensation of divine, loving energy of a spiritual nature. One study showed that engaging in spiritual community by attending religious services can extend your life by up to 14 years, so it’s unsurprising that connecting with the Divine—whether within yourself or in spiritual community with others who share your faith—would activate your body’s self-repair mechanisms so your body can heal itself. 

    3. They felt love, joy, and happiness.

    Many of those Dr. Turner interviewed credited their cancer cure with increasing love and happiness in their lives. Studies show that happy people live up to ten years longer than unhappy people and optimists have a 77% lower risk of heart disease when compared to pessimists, most likely because feelings of joy, love, connection, optimism, and happiness flip off harmful stress responses and activate healing relaxation responses in the body, filling the body with healing hormones like oxytocin, dopamine, nitric oxide, and endorphins which bathe every cell in the body (including the cancer cells) and activate the body’s natural cancer-fighting abilities. 

    4. They released repressed emotions.

    Many of Dr. Turner’s interviewees believed that it was healing for them to release any negative emotions they'd been harboring, such as fear, anger, grief, or resentment.  We know that repressed emotions, whether they exist in the conscious or subconscious mind, act as triggers to the amygdala in your limbic brain, since the amygdala inaccurately perceives these negative thoughts as a threat to your safety. 
    Every time you feel fear, anger, grief, resentment, loneliness, pessimism, depression, or anxiety, these negative thoughts activate the “fight-or-flight” stress response that fills the body with poisonous stress hormones and deactivates the body’s natural healing processes. Dealing with your negative emotions in healthy ways—via psychotherapy, somatic work, the Hoffman Process, or any number of other modalities, can calm your amygdala, return your nervous system to its homeostatic relaxed state, and boost your body’s self-repair mechanisms.

    5. They took herbs or vitamins.

    Dr. Turner’s interviewees took various forms of herbs, vitamins, and supplements with the belief that they would help to detoxify the body and/or boost the immune system. (There wasn’t any one magic supplement that beat out the rest.) Whether these herbs, vitamins, and supplements actually helped cure the cancer—or whether they effectively helped flip on the body’s natural self-repair via the placebo effect—has yet to be determined. And it shouldn’t matter. 
    We know that 18 to 80% of the time, patients taking sugar pills with no inactive ingredients get better because they believe they're getting the real treatment. In other words, if you believe some herb, tea, tonic, vitamin, or nutritional supplement holds the key to your cure, by all means, take it. 

    6. They used intuition to help make treatment decisions.

    Those who Dr. Turner interviewed talked about the importance of following their intuition with regard to treatment-related decisions, which makes sense physiologically. When rats with a certain type of cancer are exposed to shocks, studies show that the rats who learn to escape the shocks die of cancer 30% of the time, compared to a 73% death rate when the rats become passive and just lay down and accept their fate.
    In other words, your body is your business. Whether or not you’re pursuing conventional cancer treatment or trying alternatives like the people in Dr. Turner’s study, you can’t just hand the fate of your body over to someone else the way you would hand your car over to a doctor. You know your body better than any doctor does, and following your intuition is key when it comes to fighting any illness, especially cancer. If you or someone you love has cancer, the very act of taking charge of your health not only ensures that you get the best care; it also gives you a survival advantage and makes it more likely that you will become one of the medical miracles. 

    It’s Not Just Treatment, It’s Prevention

    Remember, these healthy behaviors aren’t just about helping you experience an unexpected remission. They’re about prevention. After all, this is your LIFE we’re talking about.
    If you are making this journey as I am, may God bless you with HIs healing touch. I know He loves you.









    Thursday, July 21, 2016

    Current Facts and Figures 7/19/2016

    Scripture of the Day:

    Matthew 8:7

                And Jesus saith unto him, I will come and heal him.


    Information about breast cancer seems to change on a weekly basis if not a daily basis. It is so hard to keep up. I have downloaded an article that gives the current information as of July 19, 2016. There is some reading to be done here and the link will be provided. I just want to highlight some of what is said.

    This publication attempts to summarize current scientific information about breast cancer. Except when specified, it does not represent the official policy of the American Cancer Society. Suggested citation: American Cancer Society. Breast Cancer Facts & Figures 2015-2016. Atlanta: American Cancer Society, Inc. 2015.

    What is breast cancer? Cancer is a group of diseases that cause cells in the body to change and grow out of control. Most types of cancer cells eventually form a lump or mass called a tumor, and are named after the part of the body where the tumor originates. The vast majority of breast cancers begin in the parts of the breast tissue that are made up of glands for milk production, called lobules, and ducts that connect the lobules to the nipple. The remainder of the breast is made up of fatty, connective, and lymphatic tissues. Breast cancer is typically detected either during a screening examination, before symptoms have developed, or after a woman notices a lump. Most masses seen on a mammogram and most breast lumps turn out to be benign; that is, they are not cancerous, do not grow uncontrollably or spread, and are not life-threatening. When cancer is suspected, microscopic analysis of breast tissue is necessary for a definitive diagnosis and to determine the extent of spread (in situ or invasive) and characterize the type of the disease. The tissue for microscopic analysis can be obtained via a needle or surgical biopsy. Selection of the type of biopsy is based on individual patient clinical factors, availability of particular biopsy devices, and resources.

    This information given is not necessarily new. but I felt important enough to share. The following chart is information that is new and interesting.

    Table 1. 
    Estimated New Female Breast Cancer Cases and Deaths by Age, US, 2015* Age In Situ Cases Invasive Cases Deaths 
    Age              In Situ Cases              Invasive Cases              Deaths  
    <40               1,650                          10,500                           1,010
    40-49            12,310                        35,850                           3,690
    50-59            16,970                        54,060                           7,600
    60-69            15,850                        59,990                           9,090
    70-79             9,650                         42,480                           8,040
    80+                3,860                         28,960                           10,860
    All Ages        60,290                       231,840                         40,290

    I fall into the 60-69 category. These numbers are frightening to me.




    What are the signs and symptoms of
    breast cancer?

    What are the signs and symptoms of
    breast cancer?

    Breast cancer typically produces no symptoms when the tumor is small and most easily treated. Therefore, it is very important for women to follow recommended screening guidelines for detecting breast cancer at an early stage. When breast cancer has grown to a size that can be felt, the most common physical sign is a painless lump. Sometimes breast cancer can spread to underarm lymph nodes and cause a lump or swelling, even before the original breast tumor is large enough to be felt. Less common signs and symptoms include breast pain or heaviness; persistent changes to the breast, such as swelling, thickening, or redness of the breast’s skin; and nipple abnormalities such as spontaneous discharge (especially if bloody), erosion, or retraction. It is important to note that pain (or lack thereof) does not indicate the presence or the absence of breast cancer. Any persistent change in the breast should be evaluated by a physician as soon as possible.

    This article goes on for 44 pages as a PDF download. Some of it is old news but some of it is very interesting and somewhat depressing. I'll finish with this chart that breaks down some of the statistics by state:




    This link will take you to the site that I used for this information. You may find more information pertaining to you specifically.


    If you are making this journey as I am, may God bless you with His healing touch. I know He loves you.


    Sunday, July 17, 2016

    There IS Life after Letrozole.

    Scripture of the Day:

    Matthew 4:23        
    And Jesus went about in all Galilee, teaching in their synagogues and preaching the Gospel of the Kingdom and healing all manner of sickness and all manner of disease among the people

    I have been off of Letrozole for a little better than a month. Today, we went to an estate sale auction. These can be all day events and I usually don't make it the whole day! We got there at 9 AM and at noon i realized that I'd been there for 3 hours and hadn't sat down once!! I didn't have any pain usually caused by the Letrozole and sometimes I'd get winded. I ended up lasting the whole day and bidding on the things I wanted where before I just couldn't last until they got to my item. What a glorious feeling and what a wonderful day.

    4/24/2016

    I am curious about what it will be like to go off my Letrozole in August. My doctor has given me the choice. So I started looking at what some people are saying about it. I am so tired of the pain that comes with the medication. I am also curious about weight loss. I have not found anything on that yet. The sites I have looked at say that weight gain is one of the side effects. I can tell you that I went to a Rec Center 5 days a week for 7 months and only lost 8 pounds. So I'm hoping for a change in that area. 

    If this is a concern for you there are certainly more than one site with discussions about stopping that medication. I have not, as yet found any medical information about it. 

    Going off Letrozole - this is the link where I found this information. 


    Going off Letrozole (Femara) after 5-1/2 years

    by artgirl2014 on Wed Nov 12, 2014 10:59 PM
    Quote | Reply

    In 2008 I was diagnosed with breast cancer.  I had a mastectomy and was placed on Femara (Letrozole).  I stayed on it faithfully for 5 + years but decided about 6 months ago to stop.  My oncologist gave me some information on research showing that patients who remain on these AI drugs have a decreased chance of recurrence in 10 years.  Since I am 65, I am very concerned about my bone health and because of the Letrozole, I now have severe osteoporosis.  I also suffered from a considerable amount of joint pain and other less serious side effects.  If you have had a similar experience and chose the same path, how are you doing and are you relieved that you made the decision to stop?  I am busy second-guessing myself right now and would like to hear from others!  Thank you!

    RE: Going off Letrozole (Femara) after 5-1/2 years

    by ljt33 on Wed Nov 12, 2014 11:41 PM
    Quote | Reply

    I am compelled to write, because I too was diagnosed with BC in 2008, had a mastectomy, chemo, radiation, and then 5 years of tamoxifen.  I am now 53.  In April, I was running 3-4 miles a few times a week, was down around 153, and generally feeling great.  My doctor said that "studies have shown" that after 5 years of tamoxifen, one in my demographic should switch to 5 years of Femara, so I did -- around May of this year.  By mid-June, I had many aches and pains, could barely run around the block, and had gained 10 pounds.  I sought treatment from PT and orthopedic specialists, thinking that it was from too much running.... but secretly, I blamed the Femara.  That was the only change in my life right then!
    With my doctor's ok, I went off the Femara at the end of July, and then went 3 months not taking anything.  I'm back to running, albeit I have to build myself back up, but at least it is relatively painfree.
    I do not think you are crazy to go off the Femara.  It will be interesting to see if, in a few months, some of your joint pain and other things go away.  If so, it might be worth it just for that.  If you change your mind, I'm sure you could go back on it.  But I would also ask if there were any other drugs with the same/similar effect.  I am back on Tamoxifen, which I find is just fine.  The aches and pains on Femara though were negatively affecting my life!

    RE: Going off Letrozole (Femara) after 5-1/2 years

    by ljt33 on Wed Nov 12, 2014 11:43 PM
    Quote | Reply
    Ooops - I overlooked your statement that you had already stopped Femara 6 months ago.  Has your joint pain subsided as well?

    RE: Going off Letrozole (Femara) after 5-1/2 years

    by artgirl2014 on Wed Nov 12, 2014 11:48 PM
    Quote | Reply
    Much better.   Still some pain but so much better than it was!  Thanks so much for responding.  I was a runner, earlier in my life.  It was the one exercise that made any sense to me.  It was very organic in a way --- like I was connecting to all those who ran before me and before all of the health clubs and exercise equipment.

    RE: Going off Letrozole (Femara) after 5-1/2 years

    by mlbieds on Thu Nov 13, 2014 12:27 AM
    Quote | Reply
    I was diagnosed in November 2007, was lucky to have lumpectomy and radiation, followed by Tamoxifen. Tamoxifen was easy for me, until I broke my leg and then got a blood clot. The docs blamed Tamoxifen for the blood clot, and switched me to Arimidex. I stayed on it about a year and was having so much joint pain my Doc switched me to Femara. I hated it too. There were days I could hardly get out of bed, and the first ten feet or so of walking were excruciating, but got better the longer I walked. After five years (total for all drugs) I decided to go off the Femara. My onco doc wanted me to complete five years on the Femara (in addition to the 2.5 years I was on Tamoxifen and Arimidex). I said no. This was about a year ago. A lot of my joint pain went away, but not all of it. I recently had a physical and found I was very low on Vitamin D. From reading on this forum, I believe it is a side effect of the Femara, and most likely the reason I still have bone/joint pain. I am working now to get my D levels up to where they should be. I am still fatigued, but have some weird blood issues to blame for that (as far as I know, not related to cancer). At the end of the day, I balanced taking the meds with quality of life, and that is something only you know best. Good luck. Mary Lou
    If you are making this journey as I am, may God bless you with His healing touch. I know He loves you.

    Thursday, July 14, 2016

    Cancer has taken another

    Scripture of the Day:


    Jeremiah 30:17
    I will restore health unto thee, and I will heal thee of thy wounds, saith the Lord, because they, called thee an Outcast, saying, This is Zion, whom no man seeketh after.



    One of the people on my prayer list page has lost her battle with cancer. Her cancer was not breast cancer, but devastating all the same. She comes from a family in which more than one is suffering for some form a cancer. Please say a little prayer for her family as they endure this tough time in their life. 

    If you are making this journey as I am, may God bless you with His healing touch. I know He loves you.

    Sunday, July 10, 2016

    Stages of Breast Cancer


    Scripture of the Day:

    Jeremiah 17:14 (NLT)
    O Lord, if you heal, I will truly be healed; if you save me, I will truly be saved. My praises are for you alone.






    Breast cancer stages

    Deciding on your treatment is going to depend on what stage 
    of breast cancer you are in. I would like to just clarify the stages
    of breast cancer. 
    Stage 0 - (noninvasive, carcinoma in situ) breast cancer
       In stage 0, there is no evedicen of cancer cells breaking out 
       of the part of the breast in which they started, or of getting
       through to or invading neighboring normal tissue
    Stage 1 breast cancer
       In stage 1, the tumor measures up to two centimeters and 
       no lymph nodes are involved
    Stage II breast cancer (invasive breast cancer)
       In stage II, the tumor measures between 2 to 5 centimeters, 
       or the cancer has spread to the lymph nodes under the arm
       on the same side as the breast cancer.
    Stage III (Locally advanced) breast cancer
       In stage III, the tumor in the breast is more than two inches 
       in diameter across the and the cancer is extensive in the
       underarm lymph nodes, or has spread to other lymph
       nodes or tissues near the breast.
    Stage IV (metastatic) breast cancer
       In stage IV, the cancer has spread beyond the breast, 
       underarm and internal mammary lymph nodes to other parts
       of the body near or distant from the breast
    Recurrent breast cancer
       In recurrent breast cancer, the name speaks for itself. 
       In recurrent breast cancer, the disease has returned in
       spite of the initial treatment.

    I have posted previously much more information about each
    stage. This is just a run-down of what the stages are. For more
    information about each stage use the following link and then 
    click on the links provided for each individual stage. That 
    will be easier than trying to scroll back through my posts to
    find it. 
    If you are making this journey as I am, may God bless you 
    with His healing touch. I know He loves you.
       




    Thursday, July 7, 2016

    Doctor Blows Whistle - Shame on Him.



    Scripture of the Day:

    Isaiah 38:20 (NLT)

    Think of it – the Lord is ready to heal me! I will sing His praise every day of my life with instruments in the Temple of the Lord



    My niece found the following video on Facebook and asked me what I thought about it after I listened. It was very upsetting to me and very disconcerting. So I went looking for the video and information to post on my blog. What was even worst is the only thing that I have found is information that this video is making false statements. Please watch the video, but for the most part it says that chemotherapy is nothing more than a money-maker for the drug companies and doctors, that it doesn't work. Again...saying it doesn't work. You can see why that might upset me. I went through chemo and now they're saying it was a waist of my time?



    I'm glad I looked into it and discovered that this is misinformation. Oh yes, they are making money off of the drugs. I'm not so naive to believe otherwise. But, I believe with all of my being that the chemotherapy worked for me. Shame on companies or individuals for putting misinformation out there when it is so important to so many people.

    ORIGIN:In June 2016 several alternative health and conspiracy blogs published posts claiming that a Berkeley doctor had recently "blown the whistle" on chemotherapy as a treatment for cancer, revealing that it doesn't work 97% of the time and is only recommended due to practitioner greed (i.e., oncologists get kickbacks from suppliers).
    Most of those posts featured a video published to YouTube under the title "Chemotherapy Does NOT Work 97% of the Time and Kills 97% of the Time," a five-minute clip featuring a conversation between an interviewer and naturopathic physician Peter Glidden (in which the latter misrepresented a study to claim that "chemotherapy kills an average 97% of cancer patients") and cited the work of a Dr. Hardin Jones.
    One aspect of note is that the clip was published to YouTube in May 2014, but identical blog posts trumpeting it as a bombshell showing a doctor "blowing the lid off the scam of chemotherapy" weren't published by AnonHQ and RealFarmacy until 8 June 2016 and 10 June 2016, respectively:
    People who refuse chemotherapy treatment live on average 12 and a half years longer than people who undergo chemotherapy, says Dr. Jones.
    According to recent statistics, approximately 1 in 2 men and 1 in 3 women will develop cancer in their lifetimes. This saddening reality is made worse when it is acknowledged that modern methods of ‘treating’ the disease are often ineffective and only make the symptoms of the disease worse. In fact, according to one Berkeley doctor, chemotherapy doesn’t work 97% of the time.
    In the eye-opening video above, Dr. Hardin B. Jones, a former professor of medical physics and physiology at the University of California, Berkeley, discusses how ‘leading edge’ cancer treatmentis a sham.
    He has personally studied the life expectancy of patients for more than 25 years and has come to the conclusion that chemotherapy does more harm than good. The bone-chilling realization prompted Dr. Jones to speak out against the billion-dollar cancer industry.
    “People who refused chemotherapy treatment live on average 12 and a half years longer than people who are undergoing chemotherapy,” said Dr. Jones of his study, which was published in the New York Academy of Science.
    “People who accepted chemotherapy die within three years of diagnosis, a large number dies immediately after a few weeks.”
    According to the physician, the only reason doctors prescribe chemotherapy is because they make money from it. Such an accusation doesn’t seem unreasonable, as cancer treatment runs, on average, between $300,000 — $1,000,000 per treatment.
     Is any of this true? First off, as David Gorski wrote for Science-Based Medicine, such claims about chemotherapy by alternative medicine practitioners and aficionados are quite common and are typically misleadingly based on cherry-picked statistics, misunderstandings (or misrepresentations) of how chemotherapy works, and a focus on chemotherapy's very visible drawbacks rather than its (less-obvious) successes:
    If there’s one medical treatment that proponents of “alternative medicine” love to hate, it’s chemotherapy. Rants against “poisoning” are a regular staple on “alternative health” websites, usually coupled with insinuations or outright accusations that the only reason oncologists administer chemotherapy is because of the “cancer industrial complex” in which big pharma profits massively from selling chemotherapeutic agents and oncologists and hospitals profit massively from administering them. Usually, they boil down to two claims: (1) that chemotherapy doesn’t work against cancer (or, as I’ve called it before, the “2% gambit“) and (2) that the only reason it’s given is because doctors are brainwashed in medical school or because of the profit motive or, of course, because of a combination of the two. Of course, the 2% gambit is based on a fallacious cherry picking of data and confusing primary versus adjuvant chemotherapy, and chemotherapy does actually work rather well for many malignancies, but none of this stops the flow of misinformation.
    Chemotherapy, not surprisingly, is easy to demonize. There are few treatments that cause such odious side effects, and when taken to its fullest extreme, such as complete ablation of a cancer patient’s bone marrow in preparation for a bone marrow transplant, chemotherapy can be brutal. It’s also true that for advanced solid malignancies, it only tends to produce palliation or a prolongation in survival, not a cure, and people with cancer want a cure. Palliation just isn’t that appealing, for obvious reasons. When people think of chemotherapy, they think of hair falling out, nausea and vomiting, fatigue, and death. Since chemotherapy is often given for more advanced malignancies, it’s sometimes hard to tell how many of these symptoms (other than the hair loss) are due to the cancer and how much they are due to side effects of the chemotherapy, and many people incorrectly blame chemotherapy for the deaths of their loved ones with cancer. Also, because, like radiation therapy, chemotherapy is often given in the adjuvant setting (i.e., in addition to curative surgery in order to decrease the risk of recurrence and death), it’s very easy to produce stories in which people with cancer refuse chemotherapy and/or radiation therapy after surgery and attribute their survival not to the conventional therapy (surgery) but to whatever quackery they chose to use. When used in early stage cancer, although its relative efficacy can seem large, for example a 30% decrease in the risk of dying, if the risk of dying of cancer is only 10% to begin with, that’s only a 3% survival benefit on an absolute basis.
    In reality, the use of alternative medicine instead of effective treatment for cancer, where it’s been studied, is always associated much poorer survival, even in pancreatic cancer, for which conventional treatments don’t do so well. Still, among the treatments in the “cut, poison, burn” terminology that believers in alternative medicine like to use to describe conventionalcancer therapy, it is the “poison” that causes the most fear and is most viciously demonized in the alt-med “literature.”
     As well, the key information that none of these alternative health sites presented regarding Dr. Hardin's statements on the efficacy of chemotherapy was that they were based on work published in theTransactions of the New York Academy of Sciences way back in 1956, and a paper (not a study) titled "A Report on Cancer" that he presented at a science writers' conference on 7 March 1969. All of this material is fifty to sixty years out of date, and Hardin himself passed away in 1978, so even if he had researched cancer and chemotherapy until his dying days, all of his findings would now be upwards of forty years old. In the field of medical science that's a huge time difference, as exemplified by the plethora of now standard medical technologies that didn't emerge until 1978 or later: in vitro fertilization, MRI machines, the identification of HIV, hepatitis vaccines, the first draft of the human genome, etc.
    But even back in the 1950s and 1960s, Dr. Hardin's conclusions were highly questionable due to his use of old and flawed studies as their basis:
    Hardin Jones was working with data from very early in the last century, mainly from four studies containing the remarkable numbers of 651, 100, 64, and 100 untreated breast cancer patients along with a treated group. These were published in 1926 (!), 1937, (no reference given), and 1937 respectively. With the advanced cancers generally treated in those days, it is likely that most of these patients would be incurable even today.
    None of the studies he examined were properly controlled trials. Well-planned clinical studies of any kind were still rare in those times, and it would also have been quite unethical even then to randomise very destructive cancers to a "no treatment" group, as demanded by any reliable comparison of treated with untreated patients.
    Where, then, did the untreated patients come from? They were those who "refused operation or who had already advanced to an inoperable state." There are innumerable possible misleading influences in such studies.
    Moreover, our understanding of cancer and its treatment has advanced greatly since Dr. Hardin's days. Although what he said sixty years ago may have had at least some element of supportable plausibility to it, that information is now woefully out of date and has been supplanted by additional research and a superior understanding of cancer that has been developed in the last several decades:
    Hardin Jones' views (the documented ones, as opposed to the alleged ones) were actually not far off the planet once he is placed in the context of his times. It happens that in the late fifties and early sixties there was some 'therapeutic nihilism' in relation to the treatment of cancer, especially breast cancer [on which he focused].
    Despite numerous trials of different surgical operations for breast cancer, with and without radiotherapy, survival rates stayed frustratingly much the same (chemotherapy was still in its infancy and not mentioned at all in [his 1956 paper] — another area where truth seems to have been dealt with rather loosely).
    In addition, death rates of treated breast cancer patients did not seem to level out at those of the normal population at five or even ten years, as might be expected if patients surviving for that long were likely to be then cured.
    Hardin Jones used this and other data to build a whole statistical theory proposing that " ... the death rate for all kinds of cancer remains nearly fixed from the moment when cancer is identified ..."
    It was becoming apparent to oncologists that breast cancer could metastasise (spread to distant parts of the body) much earlier than generally thought, and that, rather unusually among cancers, the tiny occult (hidden) metastases could remain dormant for years before making themselves known. Breast cancer patients thus had to be followed up for very much longer than the usual five or ten years before they could be pronounced cured, and on the data available at that time it was difficult to know how many were being permanently cured. The biology of the disease, rather than the treatment, appeared to be the main determinant of survival.
    While Hardin Jones was part right, his data and his overly pessimistic views are very much a product of his times.
    One obvious indication of this is that the overall five year survival from breast cancer in the studies he examined was a dreadful 25%, whereas NCI statistics for 2002 give an overall (all comers) five year survival of about 80%. Some of this difference will be simply due to "lead time bias" (i.e., longer survival simply due to most cases being diagnosed earlier in the course of their illness, but it illustrates the very different times.
    Finally, although chemotherapy undeniably causes bad side effects in many cases, doesn't work well for some forms of cancer, and may be over-recommended by some practitioners, its benefits (especially in cases of breast cancer) are undeniable:
    The bottom line is that, contrary to what you will hear from cranks and alt-med supporters who believe in “alternative” cancer cures, in the case of early stage breast cancer, chemotherapy saves lives. In women with breast cancer, it decreases the risk of their dying from breast cancer by approximately one-third. This is nothing to sneeze at, as it means thousands upon thousands of women who would have died but did not, thanks to chemotherapy. This study simply represents yet another in a long line of studies, another strand in the web of evidence that support the efficacy of chemotherapy in prolonging the lives of women with breast cancer. It’s not perfect, and it has a lot of potential complications, but it works. This is but one example.
    Indeed, as [Vincent DeVita, one of the pioneers of chemotherapy] points out, besides its well-demonstrated role in treating hematological malignancies, chemotherapy now has a role in the primary treatment of advanced malignancies such as bladder cancer, breast cancer, cervical cancer, colorectal cancer, esophageal cancer, gastric cancer, head and neck cancer, nasopharyngeal cancer, non-small cell lung cancer, ovarian cancer, pancreatic cancer, and prostate cancer. It’s also used to prolong survival in the adjuvant setting for breast cancer, colorectal cancer, cervical cancer, gastric cancer, head and neck cancer, pancreas cancer, melanoma, non-small cell lung cancer, osteogenic sarcoma, and ovarian cancer.
    I realize that chemotherapy is imperfect and doesn’t work well for a lot of cancers. Many of the drugs cause bad side effects, and, as I’ve explained before, in the adjuvant setting you have to treat a lot of patients to benefit relatively few. I also realize that chemotherapy is sometimes oversold. At the same time, I also know that now is the best time there has ever been for treating cancer with drugs. Targeted agents allow us to attack more precisely the molecular derangements driving cancer growth with lower toxicity. Molecular profiling is paving the way for precision medicine, in which someday (or so we hope) we will be able to target treatments to the specific abnormalities in a specific patient’s tumor. 
    Last updated June 28, 2016


    If you are making this journey as I am, may God bless you with His healing touch. I know He loves you.